BioVectra and PhaseBio Pharmaceuticals Enter into Supply Agreement to Support Development and Commercialization of Bentracimab
PhaseBio Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on the development and commercialization of novel therapies for cardiopulmonary diseases, and BioVectra Inc., an innovative global contract development and manufacturing organization (CDMO) located in Charlottetown, PE, today announced a commercial scale supply agreement for the production of bentracimab, PhaseBio’s lead product candidate currently in a global Phase 3 clinical trial. Bentracimab is a novel, human monoclonal antibody fragment that in earlier clinical trials has shown immediate and sustained reversal of the antiplatelet effects of Brilinta® (ticagrelor).
Under the terms of the agreement, BioVectra will provide its integrated CDMO services for the manufacturing of the active pharmaceutical ingredient (API) of bentracimab for use in PhaseBio’s ongoing global clinical trials and for global commercial use upon regulatory approval. Utilizing a cost-efficient, E.coli-based manufacturing process at its manufacturing site in Windsor, Nova Scotia, BioVectra recently completed the first GMP run of bentracimab at commercial scale. Going forward, PhaseBio plans to integrate API manufactured at commercial scale at BioVectra into the ongoing Phase 2b and Phase 3 REVERSE-IT clinical trials to support global regulatory filings.
“We’re excited to be partnering with PhaseBio under this new commercial agreement for the high-volume scale-up and global supply of bentracimab,” said Oliver Technow, Chief Executive Officer of BioVectra. “BioVectra is an expert CDMO with proven, specialized capability in scaling the most complex biologic drug substances produced from fermentation. Leveraging our fully integrated approach and 50 years of experience, our highly-skilled team looks forward to continuing to make a difference in patients’ lives by delivering on and supporting PhaseBio’s global commercialization of bentracimab from our new, large-scale Microbial Biomanufacturing facility.”
CASTL launches new website
The Canadian Alliance for Skills and Training in Life Sciences (CASTL) announced this week the launch of their new website: castlcanada.ca
CASTL’s website was designed with user experience in mind, with clear paths for both “Learners” and “Employers” to navigate the site to understand the value CASTL has to offer, the available programming, as well as the information on the industry need. It will be an important tool used in CASTL promotions to provide introductory information on programming and to help key audiences stay up to date on the latest news.
As the CASTL website is meant to represent their community of partners and their needs, please feel free to send any feedback to info@castlcanada.ca.
Somru BioScience and Veeda Clinical Research announce joint venture Global Biotherapeutic Contract Research Organization (CRO) in India
Charlottetown, PE and Ahmedabad, India – Ingenuity BioSciences Pvt. Ltd – Veeda Clinical Research, one of India’s leading and largest independent contract research organization (CRO) companies, and Somru BioScience Inc., a leading Canadian-based biotechnology company based in Charlottetown, Prince Edward Island, are proud to announce the establishment of an innovation-centric bioanalytical laboratory in Ahmedabad, India.
Veeda and Somru announced the launch of their premier global centre of excellence lab under the flagship of Ingenuity BioSciences Pvt. Ltd. The Board of Directors of both companies have made a strategic alliance to expand their specialized service offerings, complementing their well-established portfolio in clinical services and bioassay kit development. This collaborative joint venture aims to capture the growing market needs of the global biosimilars market projected to grow from USD 28 billion in 2020 to USD 103 billion in 2026, with a CAGR of 24.2%. Somru BioScience and Veeda Clinical Research will have an equal partnership in the new joint venture.
“I am delighted with the fruition of our partnership with Somru BioScience which combines the strengths of our organizations to reinforce our vision of becoming the preferred research partners for innovative biopharmaceutical companies globally. The joint venture will bring Somru’s global standard, integrated bioassay capabilities to service the rapidly growing biosimilars industry in the region and, combined with Veeda’s strong clinical research credentials, will provide complete clinical development solutions to our clients,” said Ajay Tandon, Managing Director, Veeda Clinical Research.
Ingenuity BioSciences will be established as a premier and agile bioanalytical laboratory. Somru BioScience’s proprietary automation platform and cloud based Aegryris™ bioanalytical and productivity software suite will be a potential game-changer in the innovation-based drug discovery industry.
“This relationship will allow us to leverage our extensive experience as a biosimilar solution provider in this fast-emerging Asian market,” said Mohammed Moin, CEO of Somru BioScience Inc. “We are very impressed with Veeda’s track record as an excellent clinical service provider in India and are excited to be working with them.”
Ingenuity BiosSciences aims to offer end-to-end and modular technical services, encompassing both pre-clinical and clinical domains. The Ingenuity BioSciences scientific team is comprised of talented scientists with in-depth and extensive knowledge of bioassay method development and sample analysis, clinical trial management, and global regulatory requirements. Business development and technical teams are enthusiastic and excited to collaborate and serve Indian and International clients across pan-Asia and European markets. Ingenuity BioSciences’ website will be soon available and provide detailed information on service offerings.
Ingenuity BioSciences will be led by Mohammed Moin, CEO of Somru BioScience and Dr. Ravi Krovidi, CEO of Ingenuity BioSciences Pvt Ltd. The location of Ingenuity BioSciences in Ahmedabad, India, gives its clients a unique advantage of sharing the years of trust, regulatory expertise and reputation established by the Veeda Clinical Research services ecosystem.
“We look forward to closely working with biosimilar and biotherapeutics companies. Our vision is to become a preferred CRO clinical partner in product development’s success journey from early inception to product launch. The Biosimilarization wave is gaining significant traction, with several important monoclonal antibodies going off patent. We are very excited to partner with Somru team,” said Dr. Ravi Krovidi, CEO of Ingenuity BioSciences Pvt Ltd.
About Somru BioScience Inc.
Somru BioScience Inc. is an innovative biotechnology company based out of Prince Edward Island, Canada. Somru has developed a portfolio of reagents, ELISA kits, innovative biosimilar comparability tools and a cloud based Aegryris™ software suite to enable companies to significantly reduce the cost and timeline for biosimilar development. Somru technologies reduce early development risk by identifying clinically meaningful differences prior to running expensive clinical trials. The company has customers throughout North and South America, Europe, Australia, and Asia.
About Veeda Clinical Research
Veeda is a leading independent Clinical Research Organization in India conducting a diverse range of clinical studies including bioavailability and bioequivalence (BA/BE) studies, pharmacokinetics, pharmacodynamics, early to late phase clinical development and clinical endpoint studies for generic molecules, new chemical entities (NCE), and biopharmaceuticals. Veeda strives for excellence in quality and has been the partner of choice for many global pharmaceutical companies over the last 16 years. Veeda is reputed for its best-in-class scientific expertise, quality, and ethics. Veeda has an exemplary regulatory record of successfully completing USFDA, ANVISA, WHO, MHRA, AGES, ANSM, MCC, DCGI and NPRA audits to date.
5 ways to find a job in bioscience
Looking to find a job in bioscience? There are a number of avenues through the PEI BioAlliance to stay up to date on the latest opportunities and also get connected with the right people.
Jobs in the bioscience sector can range from research scientists, lab technicians, quality control managers and chemical process engineers, to maintenance and production technicians, or even business administration roles including accounting, marketing, HR, and sales.
Here are five ways to support your pursuit in finding a job in the growing bioscience sector:
1. Send in your resume
The PEI BioAlliance keeps an online resume library which is shared with hiring managers in the PEI bioscience cluster. If you are currently seeking employment, upon graduation, or for the summer months, send your resume to vivian@peibioalliance.com. Resume should be in PDF format with the file name “Resume – Your Name – Education/Credentials” and the email subject line “Add my resume to the 2021 PEI Bioscience Cluster Library.”
2. Check out the job board
Updated as positions become available, the PEI BioAlliance website has a job postings page which consolidates all open positions across the cluster, including direct links to apply. The website also provides links to learn more about the companies that are hiring.
3. Sign up for email alerts
If you’d prefer to receive real-time alerts directly in your inbox, sign up for our email notifications, where you’ll receive ongoing updates on the latest opportunities in bioscience. Sign up today by filling out our form.
4. Follow us on LinkedIn for our weekly job round-up
At the end of every week on the PEI BioAlliance LinkedIn, we post a summary of all of the new jobs that were made available the week prior. Follow us on LinkedIn, for these updates as well as all of the latest local news in the sector.
5. Stay up to date on the latest news and company expansions
One way to increase your likelihood of getting a job in the sector is to learn about all of the latest news and company expansions. Follow the PEI BioAlliance on Twitter and read the Latest News section on our PEI BioAlliance website to stay up to speed on all news, events and networking opportunities.
Finding a solution that fits
Takaya Technology’s PPE innovation supports fight against COVID-19
It started with an idea, a purpose, and a cause.
At the onset of the global pandemic, there was an immediate need for additional personal protective equipment (PPE) to support in the fight against COVID-19. Health care workers required not only a large supply of PPE, but one that would meet regulatory requirements and help keep frontline workers safe.
Noticing challenges with the available equipment, the Takaya team set out to innovate and create a more effective solution. Using their solid mix of expertise alongside their wide professional network, Nova Scotia-based Takaya Technology Inc. was formed.
The challenge with wearing masks
To protect themselves from job-related exposure risks, healthcare workers wear N95 masks which filter at least 95% of airborne particles. That said, in order to maintain this level of effectiveness, the N95 masks must fit the user’s face properly, creating an effective seal, to eliminate particles bypassing the filter material.
The problem observed by Takaya, was that some traditional N95 respirators were ill-fitting, and the ones that did fit properly caused significant discomfort and facial bruising. Seeing this, Takaya created an innovative mask design to serve the medical community, and ultimately the general public.
Their solution focuses on creating a better fitting respirator, that requires less force than traditional models. Their product also creates added comfort and increased breathability, providing a fit that isn’t compromised by the daily demands of clinical life, or even something as simple as speaking or smiling.
“Simple acts of humanity, like smiling or expressions of comfort, that often provide much needed warmth and support to vulnerable patients, can compromise the seal of traditional respirators. In a more drastic measure, we are learning that in some cases surgeons are instructed not to move their heads for the duration of their surgeries, to ensure their mask stays in place,” said Andrew MacKean, CEO, Takaya Technology. “We aim to remove unnecessary worry that these basic actions could be a threat to the care provider’s personal safety, so that focus can return to the priority of patient care.”
Takaya has filed a patent on its design and the team is focused on continuing to execute its commercialization strategy to bring the product to market.
“We had this idea that we knew would help people and address a critical challenge in this pandemic and in healthcare overall, but the key was knowing what to focus on and how to execute successfully,” said Erin MacKean, Chief Operating Officer, Takaya Technology. “Part of what has helped propel us forward so quickly is our ability to bring together the right people and access the appropriate financial, regulatory and commercialization expertise.”
That expertise is also available in-house at Takaya.
Chief Operating Officer Erin MacKean has a decade of experience commercializing medical devices, and a background in life sciences operations, marketing and product management. On the other hand, her brother, CEO Andrew MacKean is an entrepreneur with experience in finance, management consulting, operations, and product commercialization in regulated industries. Additionally, their sister Chief Medical Officer Dr. Susan Ripley, is an Acute Medicine Hospitalist and part of a group of attending physicians caring for COVID-19 patients, along with many other key contributors on the team who have helped drive the company forward.
“The medical device industry can be difficult to navigate as it is heavily regulated,” said Andrew. “At Takaya, we know that if you take the time to understand the best path, and assemble the right team, you can be successful.”
Takaya is the latest company to join Emergence, an Atlantic bioscience business incubator dedicated to assisting start-ups and growth-stage bioscience companies in efficiently bringing their products and services to market.
“We are very grateful to be working with the Emergence team as we move forward with Takaya’s plans for commercialization,” said Erin. “The team has been very responsive and supportive, and we look forward to working together to bring our product to market and make it available to serve medical communities around the world.”
For more information on Emergence, visit emergencebioincubator.com.
Change of date for VetHealth Global 2021
As a result of the global COVID-19 pandemic and with our intention to have an in-person conference, VetHealth Global, North America’s premier animal health and nutrition industry conference, has adjusted the original date and will now be hosted in Charlottetown, PEI from October 25 – 27, 2021. The preliminary conference program is available on the website.
VetHealth Global is a must-attend event for animal health and nutrition business executives, investors, and innovators. It has been recognized for its stellar list of presenters, innovative emerging company sessions, professional business partnering programming, and top-rated networking events.
Showcase your company
VetHealth Global is still seeking expressions of interest from early stage and emerging companies to present to strategic partners, investors, and collaborators during one of three showcase presentation sessions:
- Innovation Spotlight: Emerging companies with breakthrough technologies at the late pre-commercial, or early commercial phase, who are seeking investment or strategic partnerships (12 companies)
- New Products for Global Aquaculture: Health and nutrition products that address market opportunities in the rapidly expanding aquaculture industry (6 companies)
- Future Focus: High-potential start-ups and early stage companies with disruptive technologies aimed at unmet industry needs (6 companies)
Applications to present must be received by March 15, 2021. Short-listed applicants will be contacted for further assessment by the selection committee, before final decisions.
For questions, please contact jennifer@peibioalliance.com.
New OSC Call for Proposals to Build Resilience in our Ocean Sectors
Canada’s Ocean Supercluster recent announcement a one-time Call for Proposals for projects under their new Ocean Supercluster Resilience Program.
Through the Ocean Supercluster Resilience Program (OSCR), the OSC will invest up to $15 million in ocean projects that create strong collaborations and focus on the growth of multiple Canadian innovation-based companies. The OSCR acts as a hybrid of the OSC’s core programs in Technology Leadership and Innovation Ecosystem and intends to tackle significant challenges in Canada’s ocean industries and build relationships in the ocean sector.
The Ocean Supercluster Resilience Call for Proposals is an opportunity for projects that can be completed in less than 30 months. It is a deadline-driven and competitive program that aims to generate a diverse set of project ideas that:
- Address challenges impeding the launch of ocean-focused offerings into new markets;
- Leverage digital innovation and business reform to improve customer value, global competitiveness, and connectivity across and between ocean sectors; and
- Advance the ocean innovation ecosystem by creating and strengthening relationships between Canada’s private and public sectors.
Successful OSCR projects will:
- Identify a compelling industry relevant challenge;
- Solicit required industry investment;
- Identify appropriate private and public sector partners;
- Deliver direct commercial benefits to the project consortium; and
- Make a positive impact on Canada’s ocean innovation ecosystem.
The application process is now open and begins with Expressions of Interest which must be submitted by February 19, 2021 at 4 p.m. Atlantic time to be considered. For complete details, visit the OSC website.
BioVectra named as one of Atlantic Canada’s Top Employers 2021
Congratulations to BioVectra, who for the fourth consecutive year was named as one of Atlantic Canada’s Top Employers.
BioVectra Inc. is a leading bioscience business located in Prince Edward Island and Nova Scotia, focused on contract manufacturing and product development of active pharmaceutical ingredients, pharmaceutical intermediates, and bio-reagents. BioVectra is an industry leader in microbial fermentation, with 64,000 L of fermentation capacity.
Here are some of the reasons why BioVectra Inc. was selected as one of Atlantic Canada’s Top Employers (2021):
- BioVectra offers a range of financial benefits, from year-end bonuses to a defined contribution pension plan, to referral bonuses for employees who recruit candidates from their personal networks (to $2,000)
- As part of the organization’s health plan, BioVectra employees receive a health spending account of up to $400 per year as well as a separate wellness spending account of up to $250 per year
- BioVectra surveyed employees to understand their concerns and capture their feedback and quickly established a temporary work-from-home policy to help guide employees in the early days of the pandemic
New national partnership strengthens talent within Canada’s life science industry
Ottawa, January 5, 2021 — BioTalent Canada today announced a new partnership with the Canadian Alliance for Skills and Training in Life Sciences (CASTL). Offering multiple applied learning streams and pathways for individuals to kickstart careers in life sciences, CASTL joins more than 60 bio-economy companies, associations and post-secondary institutions as part of the BioTalent Canada national partnership network.
Life sciences continues to be an area of high demand, from COVID-19 vaccines and diagnostics, to understanding climate change and feeding the world sustainably. CASTL is a first-of-its-kind partnership between academia, industry, and government to address the future skills needs of the Canadian life sciences sector. It delivers on the economic and sectoral demand for individuals who are work-ready to enter, thrive and meet the needs of the Canadian bioscience industry, a key pillar of Canada’s economy.
CASTL aims to fill the talent pipeline with highly skilled and qualified candidates to meet the needs of the growing bioscience industry. Through industry-supported Workplace Integrated Learning (WIL) placements, learners will be prepared to grow a career in the bioscience sector, with a competitive edge. By collaborating on WIL placements, CASTL offers employers an early opportunity to identify potential new hires. CASTL’s unique value is its connection to industry and the rigour applied to its WIL placements.
BioTalent Canada’s recently launched “Essential Skills Fundamentals” and “Technical Skills Fundamentals” courses are best-in-class and designed with extensive input from industry as well as post-secondary academia. These courses will support CASTL’s learning streams including post-secondary learners, individuals looking to enter the life sciences industry through reskilling, as well as those currently employed in the sector, by helping them develop fundamental knowledge and skills.
“The partnership with BioTalent Canada is a great fit as we share a commitment to ensuring the pipeline of talent for industry remains flush with candidates ready to contribute to the success of the bio-economy,” says Christopher Gillis, Executive Director, CASTL. “No matter who you are, CASTL offers learners a place to kickstart or grow a career in life sciences, through specialized training.”
“BioTalent Canada is always looking for ways to strengthen its relationships with academia, industry, and government stakeholders,” says Rob Henderson, President and CEO of BioTalent Canada. “CASTL’s entire raison d’etre aligns well with our own. This partnership will be mutually beneficial as we continue our journey towards securing Canada’s place as a biotech leader.”
BioTalent Canada’s partnership network brings together bio-economy employers, national and regional associations, municipalities, post-secondary institutions, service providers and immigrant serving agencies. The PetriDish™—Canada’s only national bilingual biotech job board—connects employers to more than 17,400 skilled job seekers.
Visit biotalent.ca/partners to learn more about BioTalent Canada’s Partnership Plus Program.
About BioTalent Canada
BioTalent Canada™ is the HR partner of and catalyst for growth in Canada’s bio-economy. Our engagement with employers, associations, post-secondary institutions, immigrant serving agencies and service providers has built a dynamic network that is strengthening skills, connecting job-ready talent to industry and creating opportunities. Recently awarded a Great Place to Work® Certification, BioTalent Canada practices the same industry standards they recommend to their stakeholders.
For more information visit biotalent.ca.
About the Canadian Alliance for Skills and Training in Life Sciences
The Canadian Alliance for Skills and Training in Life Sciences (CASTL) is a first-of-its-kind partnership between academia, industry, and government to address the future skills needs of the Canadian life sciences sector.
Led by the PEI BioAlliance, along with partners Acadia University, Holland College, Université de Moncton, University of Prince Edward Island, BioTalent Canada, the National Research Council, and numerous industry partners, CASTL offers multiple applied learning streams for individuals to acquire the academic knowledge, and technical and professional skills to have a successful career in life sciences. peibioalliance.com/castl
Celebrating women-led bioscience companies
Emergence survey indicates 45% of founders and CEOs in the bioscience incubator are female
With only 16% of Canadian small and medium-sized businesses owned by women, there is still much work to do in all sectors to support the full and equal participation of women in the economy. As an Atlantic bio-business accelerator, Emergence is committed to advancing gender equity and supporting the establishment and success of women-led bioscience companies.
According to the 2019 Emergence Company Survey, 45% of the 46 companies who responded had women founders and/or CEOs.
“We are delighted in the independent survey results that demonstrate the significant role that women entrepreneurs play in driving innovation in Atlantic Canada,” said Mark Redmond, Director of Incubation Services, Emergence. “As we review the Emergence portfolio of more than 60 companies, we see the notable presence of women in advancing initiatives with an emphasis on human and animal health and nutrition.”
The innovative work of these Emergence companies, alongside their solid leadership, is critical in growing and strengthening the bioscience sector – a key pillar of the Atlantic economy. There are many examples of women-led bioscience companies making waves in the industry to celebrate.
For example, BioTraceIT™ President, CEO and co-founder Deborah Dullen has a background in both the biotech and medical device fields with additional expertise in business development, sales, R&D, and global market entry. Her company, BioTraceIT™ recently launched PainTrace® a platform for detecting and monitoring pain in people and animals.
Chinova Bioworks is transforming the food and beverage industry with a natural, clean-label shelf-life extender extracted from white button mushrooms. Their CEO and co-founder Natasha Dhayagude has a background in biochemistry and a passion for entrepreneurship, delivering on Chinova’s mission to not only deliver clean-label ingredients, but also reduce food waste.
Because Animals CEO and co-founder Shannon Falconer has a PhD in microbial chemical biology and worked as a postdoctoral fellow at Stanford University. While Because Animals may be a small company at this stage, it has a big mission: to create nutritious, sustainable, animal-free pet food using cultured meat.
These are only a few examples of the many women-led companies in Emergence including high-performers such as Nutracelle, MicroSintesis, BioSpa, StepScan, CNS-CRO, Au Naturel Solutions, SeaFord Pharmaceuticals, SomaDetect, VetNOW, Dr. AK Gordon, and more.
For CEO of BioTraceIT™ Deborah Dullen, she credits her family’s support to dream big and the importance of passing on this encouragement to others.
“Worldwide women represent nearly 30% of researchers and in the US, women hold 31% of senior business roles,” she said. “We must thank all these individuals who are trailblazers; we are standing on the shoulders of giants.”
For more information on Emergence, visit emergencebioincubator.com.